Arimidex Anastrozole: Side Effects, Uses, Dosage, Interactions, Warnings

Your doctor will monitor this carefully and can recommend additional treatment if needed. Severe renal impairment reduces total clearance of anastrozole by about 10%, but no dose adjustment is needed. If you’re breastfeeding, talk with your doctor before taking Arimidex.

• Anastrozole belongs to a group of medicines called aromatase inhibitors.
• In fact, Arimidex is recommended in current guidelines for preventing breast cancer in certain women who are at high risk for developing breast cancer.
• Do not increase your dose or use this drug more often or for longer than prescribed.
• These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

If your breast cancer is stimulated by hormones, such as estrogen, certain tests will show that the cancer cells have receptors (attachment sites) for those hormones. This type of breast cancer is called https://thephoenixitalian.com/index.php/2024/01/10/discover-the-easy-and-safe-way-to-purchase/ hormone receptor-positive (HR+). According to this review, taking an aromatase inhibitor, such as Arimidex, for 5 years reduced the risk of dying from breast cancer within the following 5 years by 40%.

How much does Arimidex increase survival?

It significantly lowers serum estradiolconcentrations and has no detectable effect on formation of adrenalcorticosteroids or aldosterone. Patients should be informedthat an increased level of cholesterol might be seen while receiving ARIMIDEX. Cytochrome P450 Based on in vitro and in vivo results, itis unlikely that co-administration of ARIMIDEX 1 mg will affect other drugs asa result of inhibition of cytochrome P450 [see CLINICAL PHARMACOLOGY]. In this trial, treatment for 12 months with ARIMIDEXalone had a neutral effect on lipid profile. Combination treatment withARIMIDEX and risedronate also had a neutral effect on lipid profile.

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Anastrozole may decrease blood flow to your heart, especially if you have ever had coronary artery disease (clogged arteries). Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Overdose Information for Arimidex

This includes side effects such as thinning and weakening of your bones and increased cholesterol levels. You’re unlikely to notice side effects such as these, but your doctor will monitor you for them. In a subsequent analysis of theATAC trial, patients in the two monotherapy arms were followed for a median of120 months (10 years).

When side effects of Arimidex may start

Here we look at how Arimidex and letrozole are alike and different. Arimidex and tamoxifen can cause some similar and some different side effects. The drug has been studied in boys ages 11 to 18 years with gynecomastia (breast growth in males). It’s also been studied in girls ages 2 to 9 years with early puberty that’s caused by McCune-Albright Syndrome. However, Arimidex wasn’t found to be effective for either of these conditions.

These are not all the possible side effects of ARIMIDEX.For more information, ask your doctor or pharmacist. Keep a list of them to showyour doctor and pharmacist when you get a new medicine. Efficacy results from the twostudies were similar as presented in Table 13.